ANSI and ISEA released their updated American National Standard for Minimum Requirements for Workplace First Aid Kits and Supplies (Z308.1-2026) on Sept. 17.
ANSI/ISEA Z308.1 is a voluntary consensus standard referenced by OSHA as a recommended minimum guideline for workplace first aid supplies. It is widely adopted across industries and has been incorporated into occupational safety regulations in numerous states.
ISEA said this sixth revision reflects the realities of today’s workplaces, where opioid overdoses now account for a significant share of on-the-job deaths, and advances guidance on bleeding control, tourniquet specifications, and emergency preparedness for mobile workers.
The updated standard helps employers select and maintain workplace first aid kits based on anticipated hazards and response needs. The standard establishes minimum requirements for kit contents, classification, labeling, and performance across a variety of work environments.
ISEA said the update provides clearer requirements and guidance to help employers maintain first aid supplies that match their workplace hazards and needs, including:
| Topic | Change |
|---|---|
| Naloxone | Recommends at least two naloxone nasal sprays in a clearly-labeled kit kept near other emergency supplies for opioid emergency response |
| Tourniquet specifications | Clarified to distinguish arterial tourniquets from the elastic bands used for drawing blood, which are not effective at stopping blood loss. The standard also flags a proliferation of counterfeit tourniquets as an active concern for employers. |
| Bleeding control | Now addresses supplemental bleed control kits - including chest seals, hemostatic bandages, compression bandages, and thermal blankets - for employers in higher-risk environments. |
| Mobile and field workers | Now addresses how to assess hazards across changing job sites, when to bring first aid kits from vehicles to worksites, and how to manage restocking in the field. |
| First aid training and emergency response readiness | Added to cover CPR and AED preparedness, staffing levels for trained responders, product-specific awareness training, and more. |
| Anti-choking devices | Updated guidance on anti-choking devices as supplemental supplies. |
| First Aid Guide | Guide that accompanies each first aid kit must now be provided in both English and Spanish. |
“Conformance to ANSI/ISEA Z308.1-2026 gives employers confidence that their workplace first aid supplies are aligned with current best practices and evolving occupational risks,” said Todd Van Houten, Chair of the ISEA First Aid Product Group, and Senior Director Digital Customer Experience at Cintas. “This important revision helps organizations move beyond minimum compliance toward a more effective emergency response strategy - whether that means treating severe bleeding, supporting mobile workers, or responding to an opioid overdose before EMS arrives.”
One of the most significant updates is the inclusion of naloxone - an opioid overdose reversal medication - as a recommended item in or near workplace first aid kits. Workplaces are encouraged to keep at least two naloxone nasal sprays in a clearly labeled kit near other emergency supplies, stored in plain view
The update arrives at a pivotal moment. According to U.S. Centers for Disease Control and Prevention (CDC) data, almost 80,000 people died from drug overdoses in 2024, with over half involving opioids. But according to a National Safety Council (NSC) survey, only 28% of employers reported stocking naloxone at all worksites.
“First aid supplies should be ready for the emergencies most likely to happen in your workplace,” said Cam Mackey, President & CEO of ISEA. “For millions of American workers, that now includes an opioid overdose. This revised standard reflects that reality.”
The timing aligns with growing legislative momentum:
The updated ISEA standard gives employers a voluntary framework to get ahead of that regulatory curve now.


The American National Standards Institute (ANSI) is a private, non-profit organization that administers and coordinates the U.S. voluntary standards and conformity assessment system.
Donald Halsing is the Founding Editorial Director of Work Safety 24/7. He was formerly the Associate Editor of Robotics 24/7.
Don's experience spans the supply chain, logistics, and construction industries, having worked in both warehouse operations and land surveying. He is also a professional wedding photographer with his fiancée Ashley.

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